PhenoAge Calculator (Levine 2018)
Calculate your PhenoAge biological age using nine standard blood biomarkers and the published Levine 2018 formula. Save results to track aging over time and get AI-personalized interventions to close the gap.
Formula: Levine ME et al., Aging (Albany NY), 2018 — PMID 29676998.
Enter Your Biomarkers
What is the PhenoAge Calculator?
PhenoAge is a biological age estimate developed by Dr. Morgan Levine and colleagues at Yale in 2018. It combines nine common blood biomarkers with chronological age into a single number that predicts 10-year all-cause mortality more accurately than chronological age alone. A 50-year-old with a PhenoAge of 43 has lower mortality risk than the average 50-year-old peer; a 50-year-old with a PhenoAge of 58 is biologically aging faster. The formula is published, transparent, and runs entirely in your browser — no data leaves your device.
How to Read Phenotypic Age Acceleration
The most actionable number this tool produces is age acceleration — your PhenoAge minus your chronological age. Negative values mean you are biologically younger than your birthdays suggest. Positive values mean accelerated aging, usually driven by chronic inflammation (CRP), poor glucose control, immune stress (low lymphocyte %, high WBC), or red-cell dysfunction (high RDW). Each year of positive acceleration corresponds to roughly 9–10% higher 10-year mortality risk relative to a same-age peer.
How to Lower Your PhenoAge
Interventions with the strongest evidence: 150 minutes per week of Zone-2 cardio, two resistance-training sessions weekly, 7–9 hours of consistent sleep, daily protein around 1.6 g/kg body weight, omega-3 EPA+DHA at 2 g/day, and a Mediterranean or DASH-style anti-inflammatory diet. CRP, fasting glucose, and WBC respond within 8–12 weeks to these changes. Save your panel each test to watch the trend. Most users see PhenoAge drop 1–3 years within six months of consistent change.
PhenoAge vs DunedinPACE vs GrimAge
PhenoAge is the easiest biological-age clock to self-calculate because it only requires a standard chemistry and CBC blood panel that any clinic runs for under $100. DunedinPACE and GrimAge use DNA methylation patterns from saliva or blood and require specialized labs (TruDiagnostic, Elysium Index) at $200–$500 per test. Methylation clocks measure pace of aging more precisely, but PhenoAge correlates strongly with them and is the best free starting point for tracking change.