Semaglutide Dosage Calculator
Calculate your semaglutide injection volume and syringe units based on vial concentration and prescribed dose. View the standard titration schedule with your current phase highlighted. For informational purposes only. 100% private — nothing leaves your browser.
How Semaglutide Dosing Works
Semaglutide is a GLP-1 receptor agonist prescribed for type 2 diabetes (Ozempic) and weight management (Wegovy). It is injected subcutaneously once weekly. The dose is gradually increased over several months through a process called titration, which allows your body to adjust and minimizes gastrointestinal side effects like nausea. Understanding how to convert your prescribed milligram dose into the correct syringe units is essential for safe self-injection, especially when using compounded semaglutide from a vial rather than a pre-filled pen.
Understanding Titration Schedules
The standard semaglutide titration schedule starts at 0.25 mg per week for the first four weeks, then increases to 0.5 mg for weeks five through eight. After that, the dose increases every four weeks: 1 mg for weeks nine through twelve, 1.7 mg for weeks thirteen through sixteen, and finally the maintenance dose of 2.4 mg from week seventeen onward. Your prescriber may modify this schedule based on your tolerance and treatment goals. For Ozempic (diabetes), the maximum dose is typically 2 mg. For Wegovy (weight loss), the target maintenance dose is 2.4 mg. Never increase your dose faster than prescribed, as this significantly increases the risk of side effects.
Converting Milligrams to Syringe Units
When using compounded semaglutide from a vial, you need to calculate how much liquid to draw into your syringe. The formula is straightforward: divide your prescribed dose in milligrams by the vial concentration in mg/mL to get the volume in milliliters. Then multiply by the syringe capacity to get the number of units to draw. For example, if your dose is 0.5 mg and your vial is 2.5 mg/mL, you need 0.2 mL, which is 20 units on a 100-unit (1 mL) syringe. Different syringe sizes have different unit markings: a 0.3 mL syringe has 30 units, a 0.5 mL syringe has 50 units, and a 1 mL syringe has 100 units. Always use the smallest syringe that accommodates your volume for the most accurate measurement.
Weight Loss vs Diabetes Dosing
Semaglutide is marketed under different brand names for different conditions. Ozempic is approved for type 2 diabetes at doses up to 2 mg weekly, while Wegovy is approved for chronic weight management at a maintenance dose of 2.4 mg weekly. Compounded semaglutide is available from compounding pharmacies at various concentrations. Regardless of the source, the titration principle remains the same: start low, increase gradually, and reach your target maintenance dose over 16-20 weeks. This calculator supports all common vial concentrations and allows custom concentrations for compounded formulations. Remember that this tool is for educational and reference purposes — always follow the specific dosing instructions provided by your healthcare provider.
Frequently Asked Questions
What is semaglutide?
Semaglutide is a GLP-1 receptor agonist medication used to treat type 2 diabetes (brand name Ozempic) and for chronic weight management (brand name Wegovy). It is injected subcutaneously once per week and works by mimicking the GLP-1 hormone to regulate blood sugar and reduce appetite.
What is the standard semaglutide titration schedule?
The standard titration starts at 0.25 mg weekly for weeks 1-4, increases to 0.5 mg for weeks 5-8, then 1 mg for weeks 9-12, 1.7 mg for weeks 13-16, and finally the maintenance dose of 2.4 mg from week 17 onward. This gradual increase minimizes gastrointestinal side effects.
How do I convert mg to syringe units?
Divide your prescribed dose (mg) by the vial concentration (mg/mL) to get the volume in mL. Then multiply by the syringe total units. For example, 0.5 mg from a 2.5 mg/mL vial = 0.2 mL = 20 units on a 100-unit syringe.
What is the difference between compounded and brand semaglutide?
Brand semaglutide (Ozempic, Wegovy) comes in pre-filled pens with fixed dose settings. Compounded semaglutide is prepared by compounding pharmacies in vials at various concentrations, requiring you to draw the correct volume with a syringe. Both contain the same active ingredient, but compounded versions may vary in concentration.
Is this calculator private?
Yes. All calculations run entirely in your browser. No health data, dosage information, or personal details are sent to any server. Your inputs are saved locally for convenience and can be cleared at any time.
Does this calculator work for Ozempic and Wegovy?
Yes. Both Ozempic and Wegovy contain semaglutide. This calculator works for any semaglutide formulation — brand-name pens or compounded vials. Simply enter your vial concentration and prescribed dose. Note that Ozempic max dose is typically 2 mg while Wegovy targets 2.4 mg.