Semaglutide Dosage Calculator & Dose Chart
Convert a prescribed semaglutide dosage in mg into mL and U-100 syringe units, and see the FDA-label dose-escalation chart for weight-management or type 2 diabetes dosing with your current week highlighted. 100% private — nothing leaves your browser.
Not medical advice. Always follow your prescriber and the label on your pen, tablets or pharmacy vial. Never change your dose based on this tool. Compounded semaglutide is not FDA-approved and concentrations vary — confirm your vial’s mg/mL with your pharmacy.
How Semaglutide Dosing Works
Semaglutide dosage is the amount of semaglutide in milligrams (mg) a prescriber sets for each dose: once weekly for injections, once daily for tablets. Treatment starts low and steps up at fixed intervals, called titration, until a maintenance dose is reached. Injections start at 0.25 mg weekly; tablets start at 1.5 mg or 3 mg daily.
Semaglutide is a GLP-1 receptor agonist used for type 2 diabetes and for chronic weight management. Branded pens deliver a fixed mg dose with each click. Compounded semaglutide comes in vials, so the mg dose has to be converted into a volume (mL) and then into the unit markings on an insulin syringe, which is what the calculator above does.
Semaglutide Dosage Chart by Product (FDA Label)
The table below summarises the dose-escalation steps in each FDA prescribing information. Your prescriber may hold a step longer if side effects are a problem.
| Product (use) | Starting dose | Escalation steps | Maintenance / maximum |
|---|---|---|---|
| Wegovy injection (weight management) | 0.25 mg weekly, weeks 1-4 | 0.5 mg (wk 5-8) → 1 mg (wk 9-12) → 1.7 mg (wk 13-16) | 2.4 mg weekly from week 17; 7.2 mg optional after 4+ weeks on 2.4 mg |
| Ozempic injection (type 2 diabetes) | 0.25 mg weekly, weeks 1-4 (starter only) | 0.5 mg; then 1 mg and 2 mg if needed, each after 4+ weeks | 0.5 mg weekly; maximum 2 mg weekly |
| Wegovy tablets (weight management) | 1.5 mg daily, days 1-30 | 4 mg (days 31-60) → 9 mg (days 61-90) | 25 mg daily from day 91 |
| Ozempic tablets, formerly Rybelsus R2 (type 2 diabetes) | 1.5 mg daily for 30 days (starter only) | 4 mg; 9 mg if needed from day 61 | 4 mg or 9 mg daily |
| Rybelsus R1 tablets (type 2 diabetes) | 3 mg daily for 30 days (starter only) | 7 mg; 14 mg if needed after 30+ days on 7 mg | 7 mg or 14 mg daily |
Sources: Wegovy injection label, FDA announcement of the 7.2 mg dose (March 2026), Wegovy label with tablets, Ozempic injection label (DailyMed), Rybelsus and Ozempic tablets label. The two tablet formulations are not interchangeable mg for mg.
Semaglutide Units to mg: Worked Examples
On a U-100 insulin syringe, 100 units always equals 1 mL, whatever the syringe size (a 0.3 mL syringe holds 30 units, a 0.5 mL syringe holds 50). So the conversion is two steps:
- mL to draw = dose (mg) ÷ vial concentration (mg/mL)
- Units = mL × 100
Working backwards, mg = units ÷ 100 × concentration. For example, 15 units from a 2.5 mg/mL vial is 0.15 mL × 2.5 = 0.375 mg.
| Dose | 2.5 mg/mL vial | 5 mg/mL vial |
|---|---|---|
| 0.25 mg | 0.10 mL = 10 units | 0.05 mL = 5 units |
| 0.5 mg | 0.20 mL = 20 units | 0.10 mL = 10 units |
| 1 mg | 0.40 mL = 40 units | 0.20 mL = 20 units |
| 1.7 mg | 0.68 mL = 68 units | 0.34 mL = 34 units |
| 2.4 mg | 0.96 mL = 96 units | 0.48 mL = 48 units |
Compounded products are not FDA-approved. The FDA has warned of overdoses from compounded semaglutide dosing errors, often from mixing up milligrams, milliliters and syringe units. If the units on your pharmacy label differ from this calculator, follow the pharmacy label and call them to check.
Why Titrate Slowly and What to Do After a Missed Dose
Slow titration exists to limit gastrointestinal side effects such as nausea, vomiting and diarrhoea. The Wegovy label says that if a step is not tolerated, escalation can be delayed by 4 weeks. Missed-dose rules differ by product:
- Wegovy injection: if the next dose is more than 2 days (48 hours) away, take the missed dose as soon as possible; if it is less than 2 days away, skip it and resume on the usual day. After 2 or more missed doses, ask your prescriber whether to resume or restart titration.
- Ozempic injection: take a missed dose within 5 days; after 5 days, skip it and take the next dose on the usual day.
Weight Loss vs Diabetes Dosing
The two weekly injections share an active ingredient but have different schedules. The weight-management schedule climbs every 4 weeks to a 2.4 mg maintenance dose at week 17. The type 2 diabetes schedule moves to a 0.5 mg maintenance dose at week 5 and goes up to 1 mg or 2 mg only if more glucose control is needed. Use the "Dose Schedule to Show" option above to view the one that matches your prescription. This tool is for education and reference only — always follow the dosing instructions from your healthcare provider.
Last updated: October 2026
Frequently Asked Questions
What is semaglutide?
Semaglutide is a GLP-1 receptor agonist medication used to treat type 2 diabetes (brand name Ozempic) and for chronic weight management (brand name Wegovy). It is injected subcutaneously once per week and works by mimicking the GLP-1 hormone to regulate blood sugar and reduce appetite.
What is the standard semaglutide titration schedule?
For weight management (Wegovy injection), the FDA label starts at 0.25 mg weekly for weeks 1-4, then 0.5 mg for weeks 5-8, 1 mg for weeks 9-12, 1.7 mg for weeks 13-16, and the 2.4 mg maintenance dose from week 17. For type 2 diabetes (Ozempic injection), 0.25 mg for 4 weeks is followed by 0.5 mg, with optional increases to 1 mg and then 2 mg after at least 4 weeks on each dose. The gradual increase limits gastrointestinal side effects.
How do I convert mg to syringe units?
Divide your prescribed dose (mg) by the vial concentration (mg/mL) to get the volume in mL, then multiply the mL by 100, because 100 units equal 1 mL on any U-100 insulin syringe. For example, 0.5 mg from a 2.5 mg/mL vial = 0.2 mL = 20 units, whether you use a 30, 50 or 100 unit syringe.
What is the difference between compounded and brand semaglutide?
Brand semaglutide (Ozempic, Wegovy) is FDA-approved and comes in pre-filled pens that deliver a fixed mg dose. Compounded semaglutide is made by compounding pharmacies in multi-dose vials at varying concentrations and is not FDA-approved, so you must draw the correct volume with a syringe. The FDA has reported overdoses from dosing errors with compounded products, so always confirm the units with your prescriber or pharmacy.
Is this calculator private?
Yes. All calculations run entirely in your browser. No health data, dosage information, or personal details are sent to any server. Your inputs are saved locally for convenience and can be cleared at any time.
Does this calculator work for Ozempic and Wegovy?
Yes. Both Ozempic and Wegovy contain semaglutide, and the calculator shows either dose schedule. The mg-to-units conversion is only needed for vials; branded pens deliver the dose for you. The Ozempic label maximum is 2 mg weekly, while the Wegovy maintenance dose is 2.4 mg weekly, with an optional 7.2 mg dose approved in 2026.
What is the starting dose of semaglutide?
Weekly semaglutide injections for both weight management and type 2 diabetes start at 0.25 mg once weekly for 4 weeks. Daily tablets start at 1.5 mg (Wegovy tablets and Ozempic tablets) or 3 mg (Rybelsus) for 30 days. These starter doses help your body adjust and are not meant as long-term doses.
How many units is 0.25 mg of semaglutide?
It depends on the vial concentration. On a U-100 insulin syringe, 0.25 mg is 10 units (0.1 mL) from a 2.5 mg/mL vial, 5 units (0.05 mL) from a 5 mg/mL vial, and 25 units (0.25 mL) from a 1 mg/mL vial. Always check the units written on your pharmacy label before injecting.